février 2023 #02
articles parus entre juillet et décembre 2022

 Réalisation en collaboration avec l'Unité de Soutien à la Recherche Clinique (USRC) 

Cardiologie

Transseptal versus retrograde approach for ablation of left-sided accessory pathways : impact on radiation exposure Auteur : BOUCHIAT Laetitia, Assistant spécialiste, Cardiologie, Pontoise. Journal of radiological protection, Vol. 42 n°3, DOI: https://doi.org/10.1088/1361-6498/ac84e5. Management of left-sided accessory pathways (APs) is based on catheter ablation through an antegrade or retrograde approach. Both are safe and effective but are associated with exposure to x-rays; however, recipients of ablation are generally young. We sought to evaluate the impact of the approach c... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35901783/.

Chirurgie

First evaluation of surgical safety checklist's utilisation by urological surgeons in France Auteur : BART Stéphane, PH, Urologie, Pontoise/ABDESSATER Maher, PH, Urologie, Pontoise/MICHEL Philippe, PH, Réanimation médico-chirurgicale, Pontoise. BJU international, Vol. 130 n°5. In 2010, the French National Authority for Health (HAS) implemented the operating theatre checklist (OTCL) based on the WHO report about surgical safety (SS). An evaluation of the SS list, from 2007 to 2008, showed a reduction in morbidity (from 11% to 7%) and mortality (from 1.5% to 0.8%). The OTCL... Lire la suite

Chirurgie [cardio-vasculaire]

Extra anatomic aorto-Iliac revascularization using descending thoracic aorta to bifemoral bypass in selected cases Auteur : HENTGEN Benjamin, Ass. spé., Chirurgie vasculaire et thoracique, Pontoise. Annals of vascular surgery, Vol. 86, DOI: https://doi.org/10.1016/j.avsg.2022.05.044. Background: When best medical treatment fails to relieve symptoms of aorto-iliac occlusive disease, endovascular treatment or conventional open surgery are the remaining options depending on lesions and patients' characteristics. However, in certain situations both endovascular tools and abdominal a... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35764267/.

Surgical treatment of femoral artery bifurcation without material : technique and follow-up Auteur : HENTGEN Benjamin, Ass. spé., Chirurgie vasculaire et thoracique, Pontoise/DELATTRE Maryline, Responsable USRC, USRC, Pontoise/FALLOUH Ahed, PH, Chirurgie vasculaire et thoracique, Pontoise/FEITO Boris, PH, Chirurgie vasculaire et thoracique, Pontoise. Annals of vascular surgery, Vol. 86, DOI: https://doi.org/10.1016/j.avsg.2022.04.027. Background: Complete eversion of the femoral tripod is interesting to reduce clinical consequences of wound infection, in particular for patients at a high risk (e.g., obese, diabetics, cancer). Experience and follow-up of this technique are scarce. The different technical possibilities and results ... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35513126/.

Gynécologie & obstétrique

Neonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone : a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial Auteur : PONCELET Christophe, PU-PH, Gynécologie, obstétrique, maternité, Pontoise/BOIZE Philippe, PH, Réanimation et médecine néonatales, Pontoise. The lancet, Vol. 400 n°10352, DOI: 10.1016/S0140-6736(22)01535-5. Background: Antenatal betamethasone is recommended before preterm delivery to accelerate fetal lung maturation. However, reports of growth and neurodevelopmental dose-related side-effects suggest that the current dose (12 mg plus 12 mg, 24 h apart) might be too high. We therefore investigated whethe... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35988568/.

Using magnetic resonance imaging during childbirth to demonstrate fetal head moldability and brain compression : prospective cohort study Auteur : AMI Olivier, PA, Gynécologie, obstétrique, maternité, Pontoise. JMIR formative research, Vol. 6 n°11, DOI: https://doi.org/10.2196/27421. Background: Childbirth is a physiological process with significant medical risk, given that neurological impairment due to the birthing process can occur at any time. Improvements in risk assessment and anticipatory interventions are constantly needed; however, the birthing process is difficult to a... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36322921/.

Hématologie

AML with inv(16)/t(16;16) and high-risk cytogenetic abnormalities : atypical features and unfavorable outcome Auteur : GUIGNEDOUX Geoffroy, PH, Hématologie biologique, Pontoise. Hematology, Vol. 27 n°1, DOI: https://doi.org/10.1080/16078454.2022.2078027. Objectives: Acute myeloid leukemia (AML) with inv(16)/t(16;16) is among the most frequent AML subtypes. It is recognized by the detection of the CBFB-MYH11 fusion which confers a favorable prognosis, irrespective of the presence of secondary cytogenetic abnormalities. However, the effect of addition... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35622005/.

Leon's helmet Auteur : GONZALEZ Hugo, PH, Hématologie clinique, Pontoise/GUIGNEDOUX Geoffroy, PH, Hématologie biologique, Pontoise. Haematologica, DOI: https://doi.org/10.3324/haematol.2022.281125. When we first saw Mr. Leon on the list of patients scheduled during our consultation, we were surprised by his age: 95 years old! The letter sent by his attending physician mentioned massive phlebitis in the left popliteal vein associated with Hb at 103 g/L, hyperleukocytosis 14 G/L with neut... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36226490/.

A randomised phase II study of azacitidine (AZA) alone or with Lenalidomide (LEN), Valproic acid (VPA) or Idarubicin (IDA) in higher-Risk MDS or low blast AML : GFM's "pick a winner" trial, with the impact of somatic mutations Auteur : BENRAMDANE Riad, PH, Hématologie clinique, Pontoise. British journal of haematology, Vol. 198 n°3, DOI: https://doi.org/10.1111/bjh.18193. In order to improve the outcome observed with azacitidine (AZA) in higher-risk Myelodysplastic syndrome (MDS), its combination with other drugs in MDS must be evaluated. So far, no combination has not been shown to be more effective than AZA alone. AZA-PLUS was a phase II trial that, in a "pick a wi... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35438802/.

Infectiologie

Tuberculosis treatment outcomes among precarious patients in France Infectious diseases now, Article sous presse, DOI: 10.1016/j.idnow.2022.08.004. Objectives : Patients lost to follow-up and treatment failure in tuberculosis disease (TB) are major public health issues. In the absence of appropriate treatment, approximately 70 % of smear-positive patients will die within 10 years of disease progression. This study, conducted in the French regio... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36064101/.

Maladie génétique

Gestion des crises vaso-occlusives par les patients atteints de drépanocytose Auteur : BARGAIN Diane, IPA, Diabétologie, Pontoise. Recherche en soins infirmiers, n°147, DOI: https://doi.org/10.3917/rsi.147.0082. Introduction : la drépanocytose, la première maladie génétique en France et dans le monde, est pourtant méconnue des soignants et du grand public. Contexte : peu d’études portent sur le quotidien des adultes atteints de drépanocytose. Objectif : cette recherche vise à décrire la gestio... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35724043/.

Microbiologie médicale

Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy Auteur : DUFOUR Nicolas, PH, Réanimation médico-chirurgicale, Pontoise. Cell reports, Vol. 39 n°7, DOI: https://doi.org/10.1016/j.celrep.2022.110825. The clinical (re)development of bacteriophage (phage) therapy to treat antibiotic-resistant infections faces the challenge of understanding the dynamics of phage-bacteria interactions in the in vivo context. Here, we develop a general strategy coupling in vitro and in vivo experiments with a mathema... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35584666/.

Neurologie

Investigating the long-term effect of pregnancy on the course of multiple sclerosis using causal inference Auteur : POTTIER Corinne, PH, Neurologie, Pontoise. Neurology, Ahead of print, DOI: https://doi.org/10.1212/wnl.0000000000206774. Background and objectives: The question of the long-term safety of pregnancy is a major concern in multiple sclerosis (MS) patients, but its study is biased by reverse causation (women with higher disability are less likely to experience pregnancy). Using a causal inference approach, we aimed to est... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36564207/.

Macroglossia : a potentially severe complication of late-onset Pompe disease Auteur : POTTIER Corinne, PH, Neurologie, Pontoise. European journal of neurology, vol. 29 n°7, DOI: https://doi.org/10.1111/ene.15330. Background: Pompe disease is a rare neuromuscular disorder caused by a deficiency of a lysosomal enzyme, acid α-glucosidase. Macroglossia is a classic clinical sign of several inherited myopathies and has also been reported to occur progressively in late-onset Pompe disease (LOPD). Methods: W... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35302691/.

Oncologie

Gilteritinib activity in refractory or relapsed FLT3-mutated acute myeloid leukemia patients previously treated by intensive chemotherapy and midostaurin : a study from the French AML Intergroup ALFA/FILO Auteur : VAIDA Ioana, PH, Hématologie clinique, Pontoise. Leukemia, Vol. 37 n°1, DOI: https://doi.org/10.1038/s41375-022-01742-7. The real-world efficacy and safety of gilteritinib was assessed in an ambispective study that included 167 R/R FLT3-mutated AML patients. Among them, 140 received gilteritinib as single agent (cohort B), including 67 previously treated by intensive chemotherapy and midostaurin (cohor... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36376378/.

ORL

Randomized trial of the effect of video training on residents' surgical skills in facial skin reconstructive surgery : a SQUIRE study Auteur : BEGON Édouard, PH, Dermatologie, Pontoise/WALTER Amélie, PH, Dermatologie, Pontoise/FAUCON Benoît, PH, Stomatologie, chirurgie maxillo-faciale, orthodontie, paradontologie, implantologie, chirurgie cervico faciale et ORL, Pontoise. European annals of otorhinolaryngology, head and neck diseases, Vol. 139 n°6, DOI: https://doi.org/10.1016/j.anorl.2022.06.002. Objectives: The purpose of this study was to evaluate the impact of facial skin reconstruction training videos for head and neck and maxillofacial surgery residents. Material and methods: This randomized trial, conducted in France, involved residents in head and neck and maxillofacial surgery... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35717531/.

Recherche médicale & paramédicale

Impact of methodological choices in comparative effectiveness studies : application in natalizumab versus fingolimod comparison among patients with multiple sclerosis Auteur : POTTIER Corinne, PH, Neurologie, Pontoise. BMC Medical research methodology, Vol. 22 n°1, DOI: https://doi.org/10.1186/s12874-022-01623-8. Background: Natalizumab and fingolimod are used as high-efficacy treatments in relapsing-remitting multiple sclerosis. Several observational studies comparing these two drugs have shown variable results, using different methods to control treatment indication bias and manage censoring. The objective... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35637426/.

Rhumatologie

Management and outcome of native joint septic arthritis : a nationwide survey in French rheumatology departments, 2016-2017 Auteur : PERTUISET Édouard, PH, Rhumatologie, Pontoise. Annals of the rheumatic diseases, Vol. 81 n°11, DOI: https://doi.org/10.1136/ard-2022-222143. Objectives: To describe current management and outcome of native joint septic arthritis (NJSA) in French rheumatology departments. Methods: For this retrospective, nationwide multicentric study, 127 French rheumatology departments were contacted to report up to 12 cases of NJSA that occurred ... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35820674/.

Sage-femme

Postnatal mental health during the COVID-19 pandemic : impact on mothers' postnatal sense of security and on mother-to-infant bonding Auteur : SCHAMING Céline, Psychologue, Maternité, Pontoise. Midwifery, Vol. 117, DOI: https://doi.org/10.1016/j.midw.2022.103557. Background: The unprecedented COVID-19 pandemic context imposed new living conditions which greatly modified women's experience of the postpartum period and brought significant changes to postnatal care. Objective: The main objective of this study was to evaluate the impact of the COVID-19 pa... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36473335/.

Urgences & réanimation

Continuous renal replacement therapy versus intermittent hemodialysis as first modality for renal replacement therapy in severe acute kidney injury : a secondary analysis of AKIKI and IDEAL-ICU studies Auteur : BOULET Éric, PH, Réanimation médico-chirurgicale, Pontoise. BMC Critical care, Vol. 26 n°1, DOI: https://doi.org/10.1186/s13054-022-03955-9. Background: Intermittent hemodialysis (IHD) and continuous renal replacement therapy (CRRT) are the two main RRT modalities in patients with severe acute kidney injury (AKI). Meta-analyses conducted more than 10 years ago did not show survival difference between these two modalities. As the quality ... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35379300/.

Impact of early limitation of therapeutic effort in elderly COVID-19 patients admitted to the intensive care unit : a cohort study Auteur : GRANT Caroline, P Cont., Rééducation post-réanimation, Beaumont sr Oise. Journal of personalized medicine, Vol. 12 n°9, DOI: https://doi.org/10.3390/jpm12091501. (1) Background: Admission to the ICU and intensity of care provided to elderly COVID-19 patients are difficult choices guided by the expected patient-centered benefits. However, the impact of an early discussion of limitation of therapeutic effort (LTE) has been poorly investigated. <br /> (2) Meth... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36143286/.

Nicotine patches in patients on mechanical ventilation for severe COVID-19 : a randomized, double-blind, placebo-controlled, multicentre trial Auteur : DUBOST Jean-Louis, PH, Réanimation médico-chirurgicale et coordination hospitalière de prélèvements d’organes et de tissus, Pontoise. Intensive care medicine, Vol. 48 n°7, DOI: https://doi.org/10.1007/s00134-022-06721-1. Purpose: Epidemiologic studies have documented lower rates of active smokers compared to former or non-smokers in symptomatic patients affected by coronavirus disease 2019 (COVID-19). We assessed the efficacy and safety of nicotine administered by a transdermal patch in critically ill patients with ... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35676335/.

Urologie

Biochemical relapse predictive factors in patients with lymph node metastases during radical prostatectomy Auteur : ABDESSATER Maher, PH, Urologie, Pontoise. Progrès en urologie, Article sous presse, DOI: 10.1016/j.purol.2022.07.141 . Introduction: There are no clear recommendations for the management of patients with lymph node invasion discovered during radical prostatectomy for prostate cancer (PCa). Adequate risk stratification could personalize post-surgical adjuvant treatment. Our objective was to identify predictive factor... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35941008/.

Les complications en chirurgie urologique : l’urologue acteur de la gestion des risques Auteur : BART Stéphane, PH, Urologie, Pontoise. Progrès en urologie, Vol. 32 n°14, DOI: https://doi.org/10.1016/j.purol.2022.08.014. La première partie de cet article traite de l’accréditation de la qualité de la pratique professionnelle des médecins urologues et des équipes médicales exerçant en établissements de santé publics ou privés. Il s’agit d’une démarche nationale volontaire de gestion des risques fondée sur la déclarati... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36410871/.

Les pratiques professionnelles des chirurgiens urologues en France concernant la check-list au bloc opératoire Auteur : ABDESSATER Maher, PH, Urologie, Pontoise/MICHEL Philippe, PH, Réanimation médico-chirurgicale, Pontoise. Progrès en urologie, Article sous presse, DOI: 10.1016/j.purol.2022.09.016. Introduction : En 2018, la HAS a intégré une phase de « time-out » ou temps de pause (TP) dans la dernière version de la check-list CL du bloc opératoire afin d’améliorer la sécurité des patients opérés. Cette étude a cherché à évaluer des pratiques professionnelles des chirurgiens urologues françai... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/36207247/.

La thymoglobuline en traitement d’induction chez les transplantés rénaux à faible risque immunologique : une expérience marocaine Auteur : ABDESSATER Maher, PH, Urologie, Pontoise. The pan african medical journal, Vol. 41 art. 138, DOI: https://doi.org/10.11604/pamj.2022.41.138.23091. Introduction: la thymoglobuline® est un anticorps polyclonal indiqué en traitement d´induction en transplantation rénale. Le but de notre travail est d´étudier l´efficacité de la thymoglobuline® en traitement d´induction chez des transplantés rénaux à faible risque immunologique. Méthodes: il s´agi... Lire la suite Lien PubMed : https://pubmed.ncbi.nlm.nih.gov/35519161/.